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KMID : 1094020120290030220
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Journal of Veterinary Clinics
2012 Volume.29 No. 3 p.220 ~ p.225
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Anesthetic and Cardiorespiratory Effects of Medetomidine-Ketamine-Butorphanol and Xylazine-Ketamine-Butorphanol in Dogs
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Lee Tae-Hun
Lee Jae-Yeon
Jeong Seong-Mok
Kim Myung-Cheol
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Abstract
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This study examined the anesthetic and cardiopulmonary effects of xylazine or medetomidine in combination with ketamine-butorphanol in dogs. Five dogs were used in both the medetomidine-ketamine-butorphanol (MKB) group and the xylazine-ketamine-butorphanol (XKB) group. The procedures for the two groups were performed 4 weeks apart. MKB group showed a shorter duration for anesthesia than XKB group. Other factors were not statistically significant between the two groups. The MKB group showed signs of bradycardia, therefore cautious patient monitoring is necesessary. The XKB showed a longer anesthetic time and less adverse effects, however the MKB combination was more expensive and had less advantages. In conclusion, the results suggested the recommended use of both MKB and XKB in procedures that need approximately 50 minutes. If patients have a risk of bradycardia, one should be cautious of using a medetomidine-xylazine-butorphanol combination. Both MKB and XKB did not have much adverse effects; however MKB did not have advantages when compared to XKB. Therefore, XKB may be more effective when compared to MKB.
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KEYWORD
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medetomidine, xylazine, ketamine, butorphanol, dogs
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